Lifetime Achievement Award

This year the Lifetime Achievement Award in Alzheimer's Disease Therapeutic Research, is awarded to Takeshi Iwatsubo MD, PhD in recognition for his pioneering work in Alzheimer's Disease neuroimaging and neuropathology

Takeshi Iwatsubo is director of the National Institute of Neuroscience, National Center of Neurology and Psychiatry, Project Professor of the University of Tokyo, and chairman of the Japan Society for Dementia Research. Trained as a neurologist and neuropathologist, Iwatsubo has contributed to the study of human neurodegenerative diseases, particularly Alzheimer's and Parkinson's, using multidisciplinary approaches. He demonstrated that Ab42 is the initial species deposited in senile plaque amyloid, elucidated the process of g-secretase complex formation, and identified phosphorylated a-synuclein as a component of Lewy bodies. He was the Principal Investigator of the Japanese AD Neuroimaging Initiative (J-ADNI) and the Japanese Trial Ready Cohort for Prevention of Alzheimer's Disease (J-TRC), and currently is the PI of the Japanese Resitry for AD-DMT. He is the recipient of the MetLife Award for Medical Research (2008), AAIC Lifetime Achievement Award (2010), the Potamkin Prize (2012), and the Medal with Purple Ribbon from the Japanese government (2024).